High intensity statin3/24/2023 We then performed logistic regressions that assessed the relation of demographic factors to high-statin, ezetimibe, PCSK9 inhibitor, and icosapent ethyl uses. The percentage of people on icosapent ethyl and with triglyceride levels less than 100 mg/dL, 100–149 mg/dL, 150 mg/dL to 199 mg/dL, and 200 mg/dL and greater were also analyzed using the Chi-squared test of proportions. We examined the percentage of people on low-, moderate-, and high-intensity statin therapy, and at LDL-C levels less than 70 mg/dL, 70–99 mg/dL, and 100 mg/dL or greater. The Chi-squared test of proportions was used to compare icosapent ethyl and statin use according to risk group, sex, and ethnicity. R programming was used for statistical analysis, utilizing the All of Us Research Program participants to project estimates to the US population. We also analyzed these parameters across health insurance status, education, and income categories. Risk factors included were age ≥60 years, hypertension (blood pressure ≥ 130/80 mmHg or being on antihypertensive therapy), low-density lipoprotein cholesterol (LDL-C) ≥ 160 mg/dL, cigarette smoking, and high-density lipoprotein cholesterol (HDL-C) < 40 mg/dL for males and <50 mg/dL for females ( Table 1). We categorized our ASCVD risk groups as moderate risk based on ≤1 CVD risk factor, high risk with ≥2 CVD risk factors, and DM with known ASCVD. Ethnicity within our cohort included non-Hispanic White, non-Hispanic Black, Hispanic or Latino, Asian, and other. We excluded participants with Type 1 DM and variables with missing values in our analysis from participants. ![]() On the researcher workbench, we created a cohort of 81,332 participants aged ≥ 18 years enrolled between 20 with DM based on ≥1 of the following from recorded personal or medical history: DM, DM without complications, type 2 DM, different diseases/conditions due to DM, secondary DM, on insulin treatment or DM medication, HbA1c ≥ 6.5%, fasting glucose ≥ 126 mg/dL, or non-fasting glucose ≥ 200 mg/dL. Moreover, clinical trials have shown that statin therapy, proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor use, and fish oil therapy using pure icosapent ethyl all reduce ASCVD risk, including among those with DM. adults aged 20 years and over with diabetes in the US National Health and Nutrition Examination Survey, approximately 40% had triglyceride levels of ≥ 150 mg/dL, regardless of statin use and even among statin users with LDL-C < 70 mg/dL, one-third had borderline or elevated levels. Hypertriglyceridemia (HTG) also remains common in patients with DM. In the US Diabetes Collaborative Registry, among the 74,393 patients with DM, 48.6% had controlled levels of low-density lipoprotein-cholesterol (LDL-C) but only 62% were on a moderate- or high-intensity statin. Dyslipidemia remains a significant ASCVD risk factor in those with DM. Guideline-recommended use of high-intensity statins and non-statin therapy among our higher risk DM patients is lacking, with LDL-C inadequately controlled.Ītherosclerotic cardiovascular diseases (ASCVD) are major causes of morbidity and mortality in people with diabetes mellitus (DM). Those with DM and ASCVD were more likely to be on high-intensity statins, ezetimibe, and icosapent ethyl. Overall, 1.9% of participants with triglycerides ≥ 150 mg/dL were on icosapent ethyl. Among those with DM and ASCVD, only 21.1% had LDL-C < 70 mg/dL. Overall, 5.1% were using ezetimibe and 0.6% PCSK9 inhibitors. Only 18.2% of those with DM and ASCVD were on high-intensity statins. A total of 31.1% had ≤1 DM risk factor, 30.3% had ≥2 DM risk factors, and 38.6% of participants had DM with ASCVD. We studied 81,332 participants with DM, which included 22.3% non-Hispanic Black and 17.2% Hispanic. We examined the use of statin and non-statin therapy as well as LDL-C and triglyceride levels. ![]() In the All of Us Research Program, we categorized DM as (1) moderate risk (≤1 CVD risk factor), (2) high risk (≥2 CVD risk factors), and (3) DM with atherosclerotic CVD (ASCVD). We studied lipid levels and treatment status in patients with DM across cardiovascular disease (CVD) risk groups and sociodemographic factors. Real-world data on lipid levels and treatment among adults with diabetes mellitus (DM) are relatively limited.
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Anytoiso core keygen3/24/2023 ![]() The app is now notarized for macOS 10.Integration with Explorer and Apple Finder.Supports DMG, RAR, 7Z, PKG (20+ extensions).Ability to convert and extract the ISO file.Connect any CD / DVD image to VMWare virtual machine.Most BURN CD / DVD software work with ISO images.8 Low Impact Exercises to Work the Core and Raise Your Heart Rate. Run on Windows and Mac OS X operating systems Destiny 2 hotfix 6 2 0 6 full patch notes Disjunction matchmaking Spark of Feedback.Supports all popular CD / DVD formats on the Internet.Get AnytoISO full version free download link v3.9.6 below.Īnytoiso Pro 3.9.6 Features (Windows/MacOSX) But why are we using ISO file actually? Because it’s simple and bootable. With this application, you can open and extract that file on Windows or MacOSX flawlessly. Just like ISO, the other format such as NRG, IMG, MDF, and others is quite well known across the world. After all, only the best ISO software could easily support any type of file format. It can create ISO from almost everything including all CD/DVD/BD images formats popular in Internet (NRG, MDF, UIF, DMG, ISZ, BIN, DAA, PDI, CDI, IMG, etc), CD/ DVD/ Blue-ray disks or simply from a local folder. Moreover, AnytoISO Professional 3.9.6 also equipped with ultra-fast performance on any hardware specification.Įven though there are many similar programs on the internet, you can’t just download and use anything without learning its capabilities. AnyToISO Professional 3.8.0 : is the one of the best ultimate ISO Creator for Windows. With its simple features, converting files becomes quite easy. ![]() When you’re asking about how to create an ISO file on Windows or macOS, the answer is using this software. Anytoiso Full Crack Free Download v3.9.6 (Win/Mac)ĪnytoISO 3.9.6 Full Version Download Free – This software is quite powerful to convert any files into ISO format, just like it’s competitor, UltraISO Software. I am fish characters3/24/2023 Cetaceans and seacows are aquatic mammals, not fish, and shellfish are mollusks, not fish, so they are therefore excluded.Īn "overly-dramatic" goldfish who is Oscar's girlfriend.įish that live in Bikini Bottom and other cities in the sea. This includes sharks and eels, both of which are fish. This is a list of fictional fish from literature, animation and movies.
Dosbox load game3/24/2023 ![]() ![]() By default, games will install to ~/Games/Heroic//. Install whichever games you want to play in DOSBox. or if your game doesn't list native Linux support but is running a version of DOSbox that doesn't work on the Steam Deck, here's a workaround. Many games will launch from here without issue, but if you want to be able to play them from game mode without having to open Heroic first. Launch the Discovery Store and then download the games. If you bought the game from GOG, you'll want the Heroic Game Launcher in order to install them. Depending on where you get your games from, we'll need to install them.įor the sake of this tutorial we will be using SimCity 2000, Aladdin, and Earthworm Jim as examples. Z:\> cd mario Z:\> mario.Are you a sucker for classic 90s games but struggling to get them to work on your Steam Deck? This guide will show you how to get them up and running in just a few minutes.įirst, if you own a DOS game through Steam, there are a few options that will help you get running really quick. Z:\> mount d ~/dosgamesĪnd then go to mario game directory and run the mario.exe file to launch the game. For games, let us use d: as virtual drive.Īt the DOSBox prompt, run the following command to mount ~/dosgames directory as virtual drive d. We have used virtual drive c: for dos programs. Now, let us see how to run a dos-based game, for example Mario Bros VGA.ĭownload Mario game from here and extract the contents in ~/dosgames directory in your Linux machine. Now you can be able to run the dos programs without any problems. To fix this, edit your ~/.dosbox/dosbox-x.xx.conf file: $ nano ~/.dosbox/dosbox-0.74.confįind the following variable and change its value from: core=auto Exit to error: DRC64:Unhandled memory reference If the game runs too fast try a fixed cycles amount in DOSBox's options. You might be encountered with following error while running turbo c or any other dos programs: DOSBox switched to max cycles, because of the setting: cycles=auto. Similarly, you can install and run other classic DOS programs. Drive C is mounted as local directory /home/sk/dosprograms. You will see an output something like below. $ ls dosprograms/tc/īGI BIN CLASSLIB DOC EXAMPLES FILELIST.DOC INCLUDE LIB README README.COMĪnd mount the ~/dosprograms directory as virtual drive C:\ in DOSBox. I have save the contents turbo c in my ~/dosprograms/TC/ directory. $ mkdir ~/dosprograms ~/dosgamesįor the purpose of this guide, let me show you how to install Turbo C program and Mario game.įirst, we will see how to install Turbo C compiler.ĭownload the latest Turbo C compiler, extract it and save the contents file in ~/dosprograms directory. The first directory is for storing programs and latter for storing games. I am going to create two directories named ~/dosprograms and ~/dosgames. Run MS-DOS Games And Programs In Linux Using DOSBoxįirst, we need to create directories to save the programs and games in our Linux system. Let us go ahead and install some DOS programs and games. Hope you learned the basic usage of DOSBox. ![]() To go back to normal screen, press ALT ENTER. Now, DosBox will start in full-screen mode. To start dosbox directly in full-screen window, edit your dosbox-x.xx.conf file and set the value of fullscreen variable as enable. To exit from DOSBox, simply type and hit ENTER: exitīy default, DOSBox starts with a normal window-sized screen like above. To launch DOSBox, run the following command from the Terminal: $ dosbox In this configuration file, you can edit/modify various settings, such as starting DOSBox in fullscreen mode, use double buffering in fullscreen, set preferred resolution to use for fullscreen, mouse sensitivity, enable or disable sound, speaker, joystick and a lot more.Īs I mentioned earlier, the default settings will work just fine. The default configuration file named dosbox-x.xx.conf exists in your ~/.dosbox folder. There is no initial configuration required to use DOSBox and it just works out of the box. ![]() On openSUSE: $ sudo zypper install dosbox Configure DOSBox On Debian, Ubuntu, Linux Mint: $ sudo apt-get install dosbox On Arch Linux and its variants like Manjaro Linux, run: $ sudo pacman -S dosbox Install Dosbox in Alpine Linux: $ sudo apk add dosbox Install DOSBox In LinuxĭOSBox is available in the default repositories of most Linux distributions. Dosbox is free, written using C programming language and distributed under GPL. Install easyhdr3/24/2023
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Nodebox 3 data visualization3/24/2023 ![]() There are many tools available for analysis at this point, for this reason one should become familiar with as many related to one’s interests before deciding to engage in advanced development. ![]() The data in turn can also be represented in the three forms No matter which type of form is analyzed, the data usually will be organized as textual data that can then be visualized and represented in some way. First I will go over the basics of data visualization to then provide a few examples of artists, designers and researchers who have implemented some form of data visualization to produce creative works of art or design. This session focuses on how data visualization relates to creative practice. You can download the technical tutorials of SVGs and a basic bar chart developed with D3, which were discussed at the end of the workshop: The notes are meant to function as an entry point for anyone who is not familiar with data visualization, but hopefully, even those who are well acquainted will find relevant some of the concepts, and especially the examples discussed. They are made available on Remix Data for those who attended the workshop, and for anyone online who may be interested in data visualization as a creative tool. ![]() The following are the notes of my presentation, part of a workshop at ADRI on October 3, 2017. Data Visualization: Research and Creative Practice In the mean time I share a list of resources that will be of use to those attending the workshop as well as anyone part of the online community who may be interested in data visualization. As before, I will be posting my presentation notes here on Remix Data soon after the presentation takes place. You could visualize data with maps, graphs, word clouds, and heat maps, for example.īelow is the JavaScript code for the frontend.For my third workshop at ADRI On October 24, I will be discussing some of my current research along with text mining methods. Note: There are many visualizations you can create with D3 beyond charting. Let’s now use D3 to create the bar chart. ![]() Notice we added an SVG element and a class class="bar-chart" to it, as we’ll load the chart as an SVG. Assuming the data from the API is the grades of some high school students, we’ll create a visualization in order to see an overview of the student’s result pattern.Īdd the following HTML code to your handlebars template: We’ll create a bar chart with the data we get from the API. In the frontend, we’ll use D3 to visualize the data. The API route will talk to a database and return the data we need to visualize in the home route. In the above code, we have an API route ( /api/data) and a home route ( /). = require('express-handlebars') Ĭonst data = // assuming this is coming from the database Or, add the following object to your package.json file and run npm install on your terminal. Run the following command to install the dependencies we’ll need to set up a basic Node application with Express and Handlebars: npm install express express-handlebars nodemon You can download it from the official website. You’ll need to have Node.js installed to follow along.
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